Iterative Synthesis of Oligo[n]rotaxanes in Excellent Yield

We present an operationally simple iterative coupling strategy for the synthesis of oligomeric homo- and hetero­[n]­rotaxanes with precise control over the position of each macrocycle. The exceptional yield of the AT-CuAAC reaction, combined with optimized conditions that allow the rapid synthesis o...

Full description

Saved in:
Bibliographic Details
Published inJournal of the American Chemical Society Vol. 138; no. 50; pp. 16329 - 16336
Main Authors Lewis, James E. M, Winn, Joby, Cera, Luca, Goldup, Stephen M
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 21.12.2016
Amer Chemical Soc
Subjects
Chemistry
Chemistry, Multidisciplinary
Physical Sciences
Science & Technology
METAL TEMPLATE SYNTHESIS
ONE-POT
INDUCED LOCALIZATION
BLOCK-SELECTED INCLUSION
SOLID-PHASE
INSULATED MOLECULAR WIRES
SUPRAMOLECULAR HYDROGELS
OXIDE) TRIBLOCK COPOLYMERS
HOST-GUEST
ANION-BINDING
Online AccessGet full text

Cover

More Information
Summary:We present an operationally simple iterative coupling strategy for the synthesis of oligomeric homo- and hetero­[n]­rotaxanes with precise control over the position of each macrocycle. The exceptional yield of the AT-CuAAC reaction, combined with optimized conditions that allow the rapid synthesis of the target oligomers, opens the door to the study of precision-engineered oligomeric interlocked molecules.
Bibliography:researchfish
UKRI
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0002-7863
1520-5126
DOI:10.1021/jacs.6b08958