Cobalt-Catalyzed Regio- and Enantioselective Allylic Amination

The first earth-abundant cobalt-catalyzed highly branched- and enantioselective allylic amination of racemic branched allylic carbonates bearing alkyl groups with both aromatic and aliphatic amines has been developed. The process allows rapid access of allylic amines in high yields with exclusively...

Full description

Saved in:
Bibliographic Details
Published inJournal of the American Chemical Society Vol. 141; no. 29; pp. 11430 - 11434
Main Authors Ghorai, Samir, Chirke, Sahadev Shrihari, Xu, Wen-Bin, Chen, Jia-Feng, Li, Changkun
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 24.07.2019
Amer Chemical Soc
Subjects
Chemistry
Chemistry, Multidisciplinary
Physical Sciences
Science & Technology
HYDROGENATION
LIGANDS
REDUCTION
ENANTIO
ALLYLATION
COMPLEXES
Online AccessGet full text

Cover

More Information
Summary:The first earth-abundant cobalt-catalyzed highly branched- and enantioselective allylic amination of racemic branched allylic carbonates bearing alkyl groups with both aromatic and aliphatic amines has been developed. The process allows rapid access of allylic amines in high yields with exclusively branched selectivity and excellent enantioselectivities (normally 99% ee) under mild reaction conditions.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0002-7863
1520-5126
DOI:10.1021/jacs.9b06035