Tracking of Mitochondrial Endogenous Ribonucleic Acid in the Cancer Cells and Macrophages Using a Novel Small-Molecular Fluorescent Probe
The expression of the genetic information on protein is achieved by mitochondrial RNA (mtRNA). However, mtRNA tracking in biological systems is bound due to the lack of an effective method. To solve this pressing problem, we construct a low molecular weight probe MR-IDE to track endogenous mtRNA in...
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Published in | Analytical chemistry (Washington) Vol. 91; no. 3; pp. 1715 - 1718 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
United States
American Chemical Society
05.02.2019
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Subjects | |
Online Access | Get full text |
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Summary: | The expression of the genetic information on protein is achieved by mitochondrial RNA (mtRNA). However, mtRNA tracking in biological systems is bound due to the lack of an effective method. To solve this pressing problem, we construct a low molecular weight probe MR-IDE to track endogenous mtRNA in the cancer cells and macrophages for the first time. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0003-2700 1520-6882 |
DOI: | 10.1021/acs.analchem.8b05305 |