Inhibition of trichothecene biosynthesis in Fusarium tricinctum by sodium bicarbonate

The effect of 0.11 M sodium bicarbonate on trichothecene mycotoxin formation was determined by analyzing cultures of Fusarium tricinctum NRRL 13426 incubated in peptone- and saccharose-supplemented Czapek-Dox broth in the presence and absence of the base. Sodium bicarbonate-treated cultures exhibite...

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Bibliographic Details
Published inJournal of agricultural and food chemistry Vol. 41; no. 12; pp. 2344 - 2346
Main Authors Roinestad, Kurt S, Montville, Thomas J, Rosen, Joseph D
Format Journal Article
LanguageEnglish
Published American Chemical Society 01.12.1993
Subjects
BICARBONATE DE SODIUM
BICARBONATO SODICO
BIOSINTESIS
BIOSYNTHESE
FUSARIUM
INHIBICION
INHIBITION
TRICHOTHECENE
TRICHOTHECENES
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Summary:The effect of 0.11 M sodium bicarbonate on trichothecene mycotoxin formation was determined by analyzing cultures of Fusarium tricinctum NRRL 13426 incubated in peptone- and saccharose-supplemented Czapek-Dox broth in the presence and absence of the base. Sodium bicarbonate-treated cultures exhibited a 7-51-fold decrease in the production of diacetoxyscirpenol (DAS) and T-2 toxin. The production of 15-acetoxyscirpenol, acetyl T-2 toxin, and neosolaniol was completely inhibited by the sodium bicarbonate. The analysis method (which could also detect 3-acetyl-DAS, deoxynivalenol, HT-2 toxin, scirpentriol, T-2 tetrol, T-2 tetraacetate, and T-2 triol) employed cold on-column capillary gas chromatography/isobutane chemical ionization ion trap mass spectrometry of the underivatized mycotoxins
Bibliography:9508121
J11
istex:3874AE7E0958154116B5462CD43EEE05AF358CF2
ark:/67375/TPS-F587R2WT-2
ISSN:0021-8561
1520-5118
DOI:10.1021/jf00036a024