A Comparison of Cerebral SPECT Abnormalities in HIV-Positive Homosexual Men With and Without Cognitive Impairment

• Published in: Archives of neurology (Chicago) Vol. 52; no. 12; pp. 1170 - 1173
• Main Authors: Sacktor, Ned, Van Heertum, Ronald L, Dooneief, George, Gorman, Jack, Khandji, Alexander, Marder, Karen, Nour, Ramy, Todak, George, Stern, Yaakov, Mayeux, Richard
• Format: Journal Article
• Language: English
• Published: Chicago, IL American Medical Association 01.12.1995
• Subjects: Adult; AIDS/HIV; Biological and medical sciences; Brain - diagnostic imaging; Brain - pathology; Cognition Disorders - diagnosis; Cognition Disorders - diagnostic imaging; Cognition Disorders - etiology; HIV Infections - complications; HIV Infections - diagnostic imaging; HIV Infections - psychology; Homosexuality, Male; Humans; Immunodeficiencies; Immunodeficiencies. Immunoglobulinopathies; Immunopathology; Linear Models; Magnetic Resonance Imaging; Male; Medical sciences; Middle Aged; Neuropsychological Tests; Organotechnetium Compounds; Oximes; Psychomotor Performance; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon; Radionuclide study; Human; Immunopathology; Homosexuality; Seropositivity; Cognitive disorder; Retroviridae; Exploration; Male; AIDS; Technetium; Immune deficiency; Photon; Infection; Virus; Viral disease; Lentivirinae; Diagnosis; Human immunodeficiency virus; Comparative study; Emission tomography

OBJECTIVE: To determine whether technetium Tc 99m exametazime (HMPAO) single-photon emission computed tomography (SPECT) can distinguish between human immunodeficiency virus (HIV)-positive homosexual men with normal neuropsychologic test results and HIV-positive homosexual men with abnormal neuropsy...