Identification of a Polymorphism in the N Gene of SARS-CoV-2 That Adversely Impacts Detection by Reverse Transcription-PCR

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Bibliographic Details
Published inJournal of clinical microbiology Vol. 59; no. 1
Main Authors Vanaerschot, Manu, Mann, Sabrina A, Webber, James T, Kamm, Jack, Bell, Sidney M, Bell, John, Hong, Si Noon, Nguyen, Minh Phuong, Chan, Lienna Y, Bhatt, Karan D, Tan, Michelle, Detweiler, Angela M, Espinosa, Alex, Wu, Wesley, Batson, Joshua, Dynerman, David, Wadford, Debra A, Puschnik, Andreas S, Neff, Norma, Ahyong, Vida, Miller, Steve, Ayscue, Patrick, Tato, Cristina M, Paul, Simon, Kistler, Amy L, DeRisi, Joseph L, Crawford, Emily D
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 17.12.2020
Subjects
Amino Acid Substitution - genetics
Commented On
Coronavirus Nucleocapsid Proteins - genetics
COVID-19 - diagnosis
COVID-19 Testing - methods
Humans
Letter to the Editor
Letters to the Editor
Polymorphism, Single Nucleotide - genetics
Reverse Transcriptase Polymerase Chain Reaction
RNA, Viral - genetics
SARS-CoV-2 - genetics
SARS-CoV-2 - isolation & purification
Sensitivity and Specificity
Viroporin Proteins - genetics
COVID-19
mutation
SARS-CoV-2
diagnosis
polymorphism
sensitivity
PCR
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Bibliography:Citation Vanaerschot M, Mann SA, Webber JT, Kamm J, Bell SM, Bell J, Hong SN, Nguyen MP, Chan LY, Bhatt KD, Tan M, Detweiler AM, Espinosa A, Wu W, Batson J, Dynerman D, CLIAHUB Consortium, Wadford DA, Puschnik AS, Neff N, Ahyong V, Miller S, Ayscue P, Tato CM, Paul S, Kistler AL, DeRisi JL, Crawford ED. 2021. Identification of a polymorphism in the N gene of SARS-CoV-2 that adversely impacts detection by reverse transcription-PCR. J Clin Microbiol 59:e02369-20. https://doi.org/10.1128/JCM.02369-20.
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.02369-20