Development of a Simple and Stable NanoESI Spray System Using Suction Wind from the MS Inlet

Improving the reproducibility of proteome analysis systems presents a challenge; therefore, in this study, we developed a new insertion spray ionization (InSpIon) system wherein an InSpIon tube was designed with a spray tip inserted into the tube. This system stabilized the spray and subsequently im...

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Bibliographic Details
Published inJournal of proteome research Vol. 22; no. 5; pp. 1564 - 1569
Main Authors Kawashima, Yusuke, Ishikawa, Masaki, Konno, Ryo, Nakajima, Daisuke, Ohara, Osamu
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 05.05.2023
Subjects
Bays
Reproducibility of Results
Spectrometry, Mass, Electrospray Ionization
Suction
Wind
nanoESI
nanoLC
K562 cells
spray InSpIon
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Summary:Improving the reproducibility of proteome analysis systems presents a challenge; therefore, in this study, we developed a new insertion spray ionization (InSpIon) system wherein an InSpIon tube was designed with a spray tip inserted into the tube. This system stabilized the spray and subsequently improved the reproducibility of the analysis.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1535-3893
1535-3907
DOI:10.1021/acs.jproteome.3c00146