Concordance for the syndrome of autism in 40 pairs of afflicted twins

The UCLA Registry for Genetic Studies in Autism was established in 1980 to test the hypothesis that genetic factors may be etiologically significant in subsets of patients. To date 61 pairs of twins have enrolled and 40 meet research diagnostic criteria for autism. The authors found a concordance fo...

Full description

Saved in:
Bibliographic Details
Published inThe American journal of psychiatry Vol. 142; no. 1; p. 74
Main Authors Ritvo, E R, Freeman, B J, Mason-Brothers, A, Mo, A, Ritvo, A M
Format Journal Article
LanguageEnglish
Published United States 01.01.1985
Subjects
Adolescent
Adult
Age Factors
Autistic Disorder - genetics
Birth Order
Child
Child, Preschool
Diseases in Twins
Female
Humans
Male
Models, Genetic
Pregnancy
Registries
Sex Factors
Twins, Dizygotic
Twins, Monozygotic
United States
United States
Online AccessGet more information

Cover

More Information
Summary:The UCLA Registry for Genetic Studies in Autism was established in 1980 to test the hypothesis that genetic factors may be etiologically significant in subsets of patients. To date 61 pairs of twins have enrolled and 40 meet research diagnostic criteria for autism. The authors found a concordance for autism in these 40 pairs of 95.7% in the monozygotic twins (22 of 23) and 23.5% in the dizygotic twins (four of 17).
ISSN:0002-953X
DOI:10.1176/ajp.142.1.74