The Use of Ammonia as an Ultimate Amino Source in the Transition Metal-Catalyzed C–H Amination

The development of efficient and elective transition metal catalyst systems enabling a direct C–H amination of hydrocarbons using ammonia is highly desirable considering the fact that ammonia is the most readily available nitrogen source. It is anticipated that a new mechanistic scaffold distinct fr...

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Bibliographic Details
Published inAccounts of chemical research Vol. 50; no. 3; pp. 482 - 486
Main Authors Kim, Hyunwoo, Chang, Sukbok
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 21.03.2017
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Summary:The development of efficient and elective transition metal catalyst systems enabling a direct C–H amination of hydrocarbons using ammonia is highly desirable considering the fact that ammonia is the most readily available nitrogen source. It is anticipated that a new mechanistic scaffold distinct from the currently applicable ones will guide this research eventually to have broad applicability in synthetic methodology, medicinal chemistry, and materials science.
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ISSN:0001-4842
1520-4898
1520-4898
DOI:10.1021/acs.accounts.6b00489