Pd(II)-Catalyzed Phosphorylation of Aryl C–H Bonds

• Published in: Journal of the American Chemical Society Vol. 135; no. 25; pp. 9322 - 9325
• Main Authors: Feng, Chen-Guo, Ye, Mengchun, Xiao, Kai-Jiong, Li, Suhua, Yu, Jin-Quan
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 26.06.2013; Amer Chemical Soc
• Subjects: Catalysis; chemical bonding; Chemistry; Chemistry, Multidisciplinary; Molecular Structure; Organometallic Compounds - chemistry; Organophosphonates - chemistry; oxides; Oxides - chemistry; Palladium - chemistry; phosphine; Phosphines - chemistry; Phosphorylation; Physical Sciences; Pyridines - chemical synthesis; Pyridines - chemistry; Science & Technology; ACIDS; PHOSPHONATION; CONSTRUCTION; DIPHENYLPHOSPHINE; ORTHO-ARYLATION; LIGAND; HYDROGEN PHOSPHATES; PHOSPHINE OXIDES; ALKENYLATION; PALLADIUM-CATALYZED ALKYLATION

A Pd(II)-catalyzed C–H phosphorylation reaction has been developed using heterocycle-directed ortho-palladation. Both H-phosphonates and diaryl phosphine oxides are suitable coupling partners for this reaction.