Examination of HIV-1 protease secondary structure specificity using conformationally constrained inhibitors

Saved in:
Bibliographic Details
Published inJournal of medicinal chemistry Vol. 34; no. 12; pp. 3395 - 3399
Main Authors Kahn, Michael, Nakanishi, Hiroshi, Chrusciel, R. Alan, Fitzpatrick, Dennis, Johnson, Michael E
Format Journal Article
LanguageEnglish
Published Washington, DC American Chemical Society 01.12.1991
Subjects
AIDS/HIV
Amino Acid Sequence
Chemistry
Drug Design
Exact sciences and technology
HIV Protease - chemistry
HIV Protease - metabolism
human immunodeficiency virus 1
inhibitors
Models, Molecular
Molecular Sequence Data
Organic chemistry
Peptides
Preparations and properties
Protease Inhibitors - chemical synthesis
Protease Inhibitors - chemistry
Protease Inhibitors - metabolism
Protein Binding
Protein Conformation
proteinase
secondary structure
specificity
Thermodynamics
use
Virus
Enzyme
Nitrogen heterocycle
Proteinase
Lactam
Retroviridae
Dipeptides
Enzyme inhibitor
Lentivirinae
Human immunodeficiency virus
Biological activity
Macrocycle
Online AccessGet full text

Cover

More Information
Bibliography:istex:3EB805D3B0556EECF2173F18B610CB2181E33D1C
ark:/67375/TPS-3TM3NZRK-6
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0022-2623
1520-4804
DOI:10.1021/jm00116a009