Clinical and psychobiological characteristics of simultaneous panic disorder and major depression

Simultaneous major depression and panic disorder appears to be a common occurrence in psychiatric patients. Patients with this condition present with more severe symptoms than patients with major depression only, respond less well to conventional antidepressants, and in general exhibit greater psych...

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Bibliographic Details
Published inThe American journal of psychiatry Vol. 145; no. 10; p. 1214
Main Author Grunhaus, L
Format Journal Article
LanguageEnglish
Published United States 01.10.1988
Subjects
Anxiety Disorders - complications
Anxiety Disorders - psychology
Depressive Disorder - complications
Depressive Disorder - psychology
Fear
Humans
Panic
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Summary:Simultaneous major depression and panic disorder appears to be a common occurrence in psychiatric patients. Patients with this condition present with more severe symptoms than patients with major depression only, respond less well to conventional antidepressants, and in general exhibit greater psychopathology over the course of their illness. Evidence suggesting a possible "dual diathesis," depression and panic, in these patients is reviewed from epidemiological, clinical, and biological perspectives. The importance of taking into account the combined symptoms in treatment planning and physiopathological studies is discussed.
ISSN:0002-953X
DOI:10.1176/ajp.145.10.1214