Lack of effect of clonidine on stuttering in children

The authors studied the effects of the alpha 2-receptor agonist clonidine on stuttering in children. Using a double-blind crossover study, they gave placebo or 4 micrograms/kg body weight per day to 25 stuttering children who were 6-13 years old. Stuttering was measured by counting the occurrences o...

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Bibliographic Details
Published inThe American journal of psychiatry Vol. 152; no. 7; p. 1087
Main Authors Althaus, M, Vink, H J, Minderaa, R B, Goorhuis-Brouwer, S M, Oosterhoff, M D
Format Journal Article
LanguageEnglish
Published United States 01.07.1995
Subjects
Adolescent
Body Weight
Child
Clonidine - administration & dosage
Clonidine - therapeutic use
Cross-Over Studies
Double-Blind Method
Drug Administration Schedule
Humans
Stuttering - drug therapy
Stuttering - psychology
Treatment Outcome
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Summary:The authors studied the effects of the alpha 2-receptor agonist clonidine on stuttering in children. Using a double-blind crossover study, they gave placebo or 4 micrograms/kg body weight per day to 25 stuttering children who were 6-13 years old. Stuttering was measured by counting the occurrences of four elementary speech difficulties and by asking parents and teachers to give an overall impression of the amount of stuttering, as well as their impression of how troublesome the stuttering was to the children. Clonidine did not improve stuttering. Clonidine cannot be recommended as a useful drug for treating children who stutter.
ISSN:0002-953X
DOI:10.1176/ajp.152.7.1087