New 5-Alkylpyrrole-2-carboxaldehyde Derivatives from the Sponge Mycale tenuispiculata

• Published in: Journal of natural products (Washington, D.C.) Vol. 63; no. 9; pp. 1318 - 1320
• Main Authors: Venkatesham, U, Rama Rao, M, Venkateswarlu, Y
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 01.09.2000; Amer Chemical Soc; American Society of Pharmacognosy
• Subjects: 5-Alkylpyrrole-2-carboxaldehydes; Analytical, structural and metabolic biochemistry; Animals; Aromatic and heterocyclic compounds; Biological and medical sciences; Chemistry, Medicinal; Fundamental and applied biological sciences. Psychology; General pharmacology; Heterocyclic compounds, pigments; Life Sciences & Biomedicine; Marine; Medical sciences; Molecular Structure; Mycale tenuispiculata; natural products; Other biological molecules; Pharmacognosy. Homeopathy. Health food; Pharmacology & Pharmacy; Pharmacology. Drug treatments; Plant Sciences; Porifera - chemistry; Pyrroles - chemistry; Pyrroles - isolation & purification; Science & Technology; Spectrum Analysis; Indian Ocean; Arabian Sea; BIOACTIVE MARINE METABOLITES; CYTOTOXIC METABOLITES; Five membered ring; Nitrile; Aliphatic compound; Nitrogen heterocycle; Animal origin; Aldehyde; Ketone; Marine environment; Porifera; Aldoxime; Isolation; Invertebrata; Ethylenic compound; Structural analysis
• ISSN: 0163-3864; 1520-6025
• DOI: 10.1021/np000101a

The sponge Mycale tenuispiculata afforded three new compounds(6‘Z)-5-(23‘-cyano-6‘-tricosenyl)pyrrole-2-carboxaldehyde (1), mycaleoxime (2), and (6‘E)-5-(6‘-penta decenyl)pyrrole-2-carboxaldehyde (3)and three known compounds, 3-formyl indole, an admixture of 5-alkyl pyrrole-2-carboxaldehydes, and thymidine. The structures of the above compounds were elucidated by the interpretation of their spectral data.