Scalarane-Based Sesterterpenes from an Indonesian Sponge Strepsichordaia aliena

• Published in: Journal of natural products (Washington, D.C.) Vol. 63; no. 10; pp. 1388 - 1392
• Main Authors: Jiménez, Jorge I, Yoshida, Wesley Y, Scheuer, Paul J, Kelly, Michelle
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 01.10.2000; Amer Chemical Soc; American Society of Pharmacognosy
• Subjects: 20,24-bishomoscalarane sesterterpenes; Analytical, structural and metabolic biochemistry; Animals; Biological and medical sciences; Chemistry, Medicinal; Fundamental and applied biological sciences. Psychology; honu'enone; Indonesia; Life Sciences & Biomedicine; Magnetic Resonance Spectroscopy; Marine; natural products; Other biological molecules; Pharmacology & Pharmacy; phyllofenone C; phyllofolactones; Plant Sciences; Porifera - chemistry; Science & Technology; Sesterterpenes; Strepsichordaia aliena; Terpenes - chemistry; Terpenes - isolation & purification; Terpenes, steroids. Hormones; Asia; Indonesia; ISEW, Indonesia; PHYLLOSPONGIA-FOLIASCENS; MARINE SPONGE; CACOSPONGIA-SCALARIS; Marine environment; Terpenoid; Porifera; Pharmacognosy; Animal origin; Isolation; Invertebrata; Sesterterpenes; Structural analysis
• ISSN: 0163-3864; 1520-6025
• DOI: 10.1021/np0000771

Investigation of the lipophilic extract of the sponge Strepsichordaia aliena revealed six new 20,24-bishomoscalarane sesterterpenes, honu'enone (1), phyllofolactones H-K (3−6), and phyllofenone C (7). Structure elucidation of these compounds was secured by spectroscopic methods, 1D and 2D NMR, and accurate mass measurements.