A current view of the interface between borderline personality disorder and depression

The recent and dramatic expansion in studies about borderline and depressive disorders is reviewed with respect to the implications about their interface. Revisiting this subject 6 years after an earlier review reveals that intervening research has altered the conclusions that should be drawn. Growi...

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Bibliographic Details
Published inThe American journal of psychiatry Vol. 148; no. 8; p. 967
Main Authors Gunderson, J G, Phillips, K A
Format Journal Article
LanguageEnglish
Published United States 01.08.1991
Subjects
Biomarkers
Borderline Personality Disorder - diagnosis
Borderline Personality Disorder - epidemiology
Borderline Personality Disorder - physiopathology
Combined Modality Therapy
Comorbidity
Depressive Disorder - diagnosis
Depressive Disorder - epidemiology
Depressive Disorder - physiopathology
Humans
Serotonin - physiology
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Summary:The recent and dramatic expansion in studies about borderline and depressive disorders is reviewed with respect to the implications about their interface. Revisiting this subject 6 years after an earlier review reveals that intervening research has altered the conclusions that should be drawn. Growing evidence from family history, comorbidity, phenomenology, psychopharmacology, biological markers, and a new domain, pathogenesis, indicates that a surprisingly weak and nonspecific relationship exists between these disorders. Implications are drawn with respect to classification, therapeutics, and defining the borderline construct.
ISSN:0002-953X
DOI:10.1176/ajp.148.8.967