Antifouling Peptide Hydrogel Based Electrochemical Biosensors for Highly Sensitive Detection of Cancer Biomarker HER2 in Human Serum

• Published in: Analytical chemistry (Washington) Vol. 93; no. 19; pp. 7355 - 7361
• Main Authors: Wang, Wenqi, Han, Rui, Chen, Min, Luo, Xiliang
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 18.05.2021
• Subjects: adsorption; Analytical chemistry; Antifouling; Antifouling substances; Biocompatibility; Biofouling; Biological properties; Biological samples; Biomarkers; Biomolecules; Biosensors; blood serum; Breast cancer; breast neoplasms; Chemistry; Conducting polymers; detection limit; Electrochemical analysis; Electrochemistry; Epidermal growth factor; ErbB-2 protein; erbB-2 receptor; Fabrication; Fluorene; fluorenes; Growth factors; humans; Hydrogels; hydrophilicity; Peptides; Polymers; Substrates

A facile strategy for the electrochemical detection of human epidermal growth factor receptor 2 (HER2), a breast cancer biomarker, was presented via the fabrication of an antifouling sensing interface based on the conducting polymer poly­(3,4-ethylenedioxythiophene) (PEDOT) and a biocompatible pepti...