Safety of Topical Corticosteroids in Pregnancy

Are topical corticosteroids safe for use in pregnancy? The available evidence found no associations of maternal use of topical corticosteroids of any potency with mode of delivery, birth defects, preterm delivery, fetal death, and low Apgar score. However, maternal use of potent to very potent topic...

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Bibliographic Details
Published inJAMA dermatology (Chicago, Ill.) Vol. 152; no. 8; p. 934
Main Authors Chi, Ching-Chi, Wang, Shu-Hui, Kirtschig, Gudula
Format Journal Article
LanguageEnglish
Published United States 01.08.2016
Subjects
Administration, Topical
Adrenal Cortex Hormones - administration & dosage
Adrenal Cortex Hormones - adverse effects
Birth Weight - drug effects
Dose-Response Relationship, Drug
Female
Fetal Death - prevention & control
Humans
Infant, Low Birth Weight
Infant, Newborn
Pregnancy
Pregnancy Outcome
Protective Factors
Risk Factors
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Summary:Are topical corticosteroids safe for use in pregnancy? The available evidence found no associations of maternal use of topical corticosteroids of any potency with mode of delivery, birth defects, preterm delivery, fetal death, and low Apgar score. However, maternal use of potent to very potent topical corticosteroids, especially when the cumulative dosage of topical corticosteroids throughout the pregnancy is very large, is associated with low birth weight.
ISSN:2168-6084
DOI:10.1001/jamadermatol.2016.1009