Using Argumentation for Absolute Reasoning about the Potential Toxicity of Chemicals

The application of a new argumentation model is illustrated by reference to DEREK for Windows, a knowledge-based expert system for the prediction of the toxicity of chemicals. Examples demonstrate various aspects of the model such as the undercutting of arguments, the resolution of multiple argument...

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Bibliographic Details
Published inJournal of Chemical Information and Computer Sciences Vol. 43; no. 5; pp. 1364 - 1370
Main Authors Judson, Philip N, Marchant, Carol A, Vessey, Jonathan D
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 01.09.2003
Subjects
Algorithms
Animals
Humans
Models, Chemical
Organic Chemicals - toxicity
Skin - drug effects
Software
Structure-Activity Relationship
Toxicology - methods
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Summary:The application of a new argumentation model is illustrated by reference to DEREK for Windows, a knowledge-based expert system for the prediction of the toxicity of chemicals. Examples demonstrate various aspects of the model such as the undercutting of arguments, the resolution of multiple arguments about the same proposition, and the propagation of arguments along a chain of reasoning.
Bibliography:ark:/67375/TPS-XW7HG9ZT-3
istex:C28E146069DEF1ACD9780CAB0E187689BBF31807
ISSN:0095-2338
1549-960X
DOI:10.1021/ci020272g