Inhibition of ongoing responses following frontal, nonfrontal, and basal ganglia lesions

The authors investigated the role of the frontal lobes and the basal ganglia in the inhibition of ongoing responses. Seventeen patients with frontal lesions (FG), 20 patients with lesions outside the frontal cortex (NFG), 8 patients with lesions to the basal ganglia (BG), and 20 orthopedic controls...

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Bibliographic Details
Published inNeuropsychology Vol. 17; no. 2; p. 272
Main Authors Rieger, Martina, Gauggel, Siegfried, Burmeister, Katja
Format Journal Article
LanguageEnglish
Published United States 01.04.2003
Subjects
Adult
Aged
Basal Ganglia - injuries
Basal Ganglia Cerebrovascular Disease - psychology
Brain Damage, Chronic - psychology
Brain Neoplasms - surgery
Cerebrovascular Disorders - psychology
Female
Frontal Lobe - injuries
Frontal Lobe - physiology
Functional Laterality - physiology
Humans
Male
Middle Aged
Neuropsychological Tests
Postoperative Complications - psychology
Psychomotor Performance - physiology
Reaction Time - physiology
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Summary:The authors investigated the role of the frontal lobes and the basal ganglia in the inhibition of ongoing responses. Seventeen patients with frontal lesions (FG), 20 patients with lesions outside the frontal cortex (NFG), 8 patients with lesions to the basal ganglia (BG), and 20 orthopedic controls (OG) performed the stop-signal task that allows the estimation of the time it takes to inhibit an ongoing reaction (stop signal reaction time [SSRT]). The FG and the BG showed significantly longer SSRTs than the OG. Within the FG, patients with right and bilateral lesions showed significantly longer SSRTs than patients with left lesions. Results provide evidence for a role of the frontal lobes and the basal ganglia in the inhibition of ongoing responses.
ISSN:0894-4105
DOI:10.1037/0894-4105.17.2.272