Amiodarone Destabilizes Intracellular Ca2+ Homeostasis and Biosynthesis of Sterols in Leishmania mexicana

• Published in: Antimicrobial Agents and Chemotherapy Vol. 53; no. 4; pp. 1403 - 1410
• Main Authors: SERRANO-MARTIN, Xenon, GARCIA-MARCHAN, Yael, FERNANDEZ, Alexis, RODRIGUEZ, Noris, ROJAS, Hector, VISBAL, Gonzalo, BENAIM, Gustavo
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.04.2009; American Society for Microbiology (ASM)
• Subjects: Amiodarone; Amiodarone - pharmacology; Animals; Antibiotics. Antiinfectious agents. Antiparasitic agents; Biological and medical sciences; Calcium; Calcium - metabolism; Cells, Cultured; Homeostasis; Homeostasis - drug effects; Leishmania mexicana; Leishmania mexicana - drug effects; Leishmania mexicana - metabolism; Macrophages - parasitology; Mechanisms of Action: Physiological Effects; Medical sciences; Mice; Microscopy, Confocal; Mitochondria - drug effects; Mitochondria - physiology; Pharmacology. Drug treatments; Sterols; Sterols - biosynthesis; Trypanosoma cruzi; Kinetoplastida; Antianginal agent; Protozoa; Calcium; Coronary vasodilator agent; Homeostasis; Amiodarone; Biosynthesis; Antiarrhythmic agent; Inorganic element; Iodine Organic compounds; Leishmania mexicana; Intracellular; Sterol
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.01215-08

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