Intramolecular Carbonylation Reactions with Recyclable Palladium-Complexed Dendrimers on Silica:  Synthesis of Oxygen, Nitrogen, or Sulfur-Containing Medium Ring Fused Heterocycles

• Published in: Journal of the American Chemical Society Vol. 127; no. 42; pp. 14776 - 14784
• Main Authors: Lu, Shui-Ming, Alper, Howard
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 26.10.2005; Amer Chemical Soc
• Subjects: Aniline Compounds - chemical synthesis; Aniline Compounds - chemistry; Catalysis; Chemistry; Chemistry, Multidisciplinary; Cyclization; Exact sciences and technology; Molecular Structure; Nitrogen - chemistry; Organic chemistry; Organometallic Compounds - chemistry; Oxygen - chemistry; Palladium - chemistry; Physical Sciences; Science & Technology; Silicon Dioxide - chemistry; Sulfur - chemistry; ENCAPSULATED PD NANOPARTICLES; TRANSITION-METAL CATALYSIS; IN-VITRO; SUPPORTED ARYLNICKEL(II) CATALYSTS; DENDRITIC CATALYSTS; ACTIVE-SITE; FUNCTIONALIZED CARBOSILANE DENDRIMERS; RECOVERABLE CATALYSTS; HYDROFORMYLATION REACTIONS; HOMOGENEOUS CATALYSIS; Intramolecular reaction; Catalytic reaction; Ether; Palladium Complexes; Catalyst selectivity; Organic ligand; Transition metal Complexes; Complex catalyst; Experimental study; Silica; Supported catalyst; Organic sulfide; Carbonylation; Tertiary amine; Platinoid Complexes; Catalyst activity; Heterocyclization; Dendritic structure
• ISSN: 0002-7863; 1520-5126
• DOI: 10.1021/ja053650h

Palladium-complexed dendrimers supported on silica were evaluated as catalysts for intramolecular carbonylation reactions. The results showed that dendritic catalysts display high activity, affording oxygen, nitrogen, or sulfur-containing seven- or eight-membered ring fused heterocycles in excellent yields. Moreover, these catalysts have competitive advantages in that they can be easily recovered by simple filtration in air and reused for up to eight cycles with only a slight loss of activity.