“Click to Chelate”: Synthesis and Installation of Metal Chelates into Biomolecules in a Single Step
Click chemistry has been employed for the assembly of novel and efficient triazole-based multidentate chelating systems while simultaneously attaching them to molecules of biological interest. The “click-to-chelate” approach offers a powerful new tool for the modification of (bio)molecules with meta...
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Published in | Journal of the American Chemical Society Vol. 128; no. 47; pp. 15096 - 15097 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
WASHINGTON
American Chemical Society
29.11.2006
Amer Chemical Soc |
Subjects | |
Online Access | Get full text |
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Summary: | Click chemistry has been employed for the assembly of novel and efficient triazole-based multidentate chelating systems while simultaneously attaching them to molecules of biological interest. The “click-to-chelate” approach offers a powerful new tool for the modification of (bio)molecules with metal chelators for potential diagnostic and therapeutic applications. |
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Bibliography: | ark:/67375/TPS-J71LQFGZ-S istex:4F31D12825A9F4B206DF2676434FB5E93B26C8C5 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0002-7863 1520-5126 |
DOI: | 10.1021/ja066779f |