Dual-Reagent Catalysis within Ir−Sn Domain:  Highly Selective Alkylation of Arenes and Heteroarenes with Aromatic Aldehydes

• Published in: Journal of organic chemistry Vol. 72; no. 8; pp. 3100 - 3103
• Main Authors: Podder, Susmita, Choudhury, Joyanta, Roy, Ujjal Kanti, Roy, Sujit
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 13.04.2007; Amer Chemical Soc
• Subjects: Aldehydes - chemistry; Alkylation; Benzene Derivatives - chemistry; Catalysis; Catalysts: preparations and properties; Chemistry; Chemistry, Organic; Exact sciences and technology; General and physical chemistry; Iridium - chemistry; Molecular Structure; Physical Sciences; Science & Technology; Stereoisomerism; Theory of reactions, general kinetics. Catalysis. Nomenclature, chemical documentation, computer chemistry; Tin - chemistry; ALCOHOLS; GOLD(III) CHLORIDE; FRIEDEL-CRAFTS ALKYLATION; EFFICIENT; Catalytic reaction; Transition element complexes; Tin compound; Iridium complex; Selectivity; Aldehyde; Alkylation; Platinoid Complexes; Aromatic compound; Catalysis; Platinoid; Tin IV Chlorides; Heterocyclic compound
• ISSN: 0022-3263; 1520-6904
• DOI: 10.1021/jo062633n

Reactions of arenes and heteroarenes with aromatic aldehydes proceeded smoothly in the presence of a catalytic combination of [Ir(COD)Cl]2−SnCl4 to afford the corresponding triarylmethane derivatives (TRAMs) in high yields. This 100% TRAM selective transformation is clean and eliminates the use of acid systems.