Total Synthesis of (±)-Kainic Acid: A Photochemical C–H Carbamoylation Approach
A novel photochemical C–H carbamoylation of an octahydroisoindole derivative with PhNCO has allowed the authors to provide a unique access to a highly functionalized proline motif from which total synthesis of (±)-kainic acid, a bioactive marine alkaloid, has been accomplished.
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Published in | Organic letters Vol. 13; no. 10; pp. 2674 - 2677 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
WASHINGTON
American Chemical Society
20.05.2011
Amer Chemical Soc |
Subjects | |
Online Access | Get full text |
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Summary: | A novel photochemical C–H carbamoylation of an octahydroisoindole derivative with PhNCO has allowed the authors to provide a unique access to a highly functionalized proline motif from which total synthesis of (±)-kainic acid, a bioactive marine alkaloid, has been accomplished. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1523-7060 1523-7052 |
DOI: | 10.1021/ol200772f |