2002 Alfred Burger Award Address in Medicinal Chemistry. Natural Products and Design:  Interrelated Approaches in Drug Discovery

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Bibliographic Details
Published inJournal of medicinal chemistry Vol. 45; no. 26; pp. 5609 - 5616
Main Author Patchett, Arthur A
Format Journal Article
LanguageEnglish
Published Washington, DC American Chemical Society 19.12.2002
Subjects
Angiotensin-Converting Enzyme Inhibitors - chemical synthesis
Angiotensin-Converting Enzyme Inhibitors - history
Antihypertensive Agents - chemical synthesis
Antihypertensive Agents - history
Awards and Prizes
Benzodiazepinones - chemical synthesis
Benzodiazepinones - history
Biological and medical sciences
Biological Products - chemistry
Biological Products - history
Chemistry, Organic
Drug Design
General pharmacology
History, 20th Century
History, 21st Century
Hydroxymethylglutaryl-CoA Reductase Inhibitors - chemical synthesis
Hydroxymethylglutaryl-CoA Reductase Inhibitors - history
Lovastatin - chemical synthesis
Lovastatin - history
Medical sciences
Patchett
Pharmacology. Drug treatments
Physicochemical properties. Structure-activity relationships
United States
Peptides
Lovastatin
Review
Research and development
Design
Teprotide
Enalapril
Peptidyl-dipeptidase A
Peptidergic receptor
Antagonist
Hormone releasing factor
Drug
Somatostatin receptor
Enzyme
Somatotropin releasing factor
Enzyme inhibitor
Natural product
CCKB cholecystokinin receptor
Statin derivative
Biological activity
Peptidases
CCKA cholecystokinin receptor
Hydrolases
Peptidyl-dipeptidases
Hydroxymethylglutaryl-CoA reductase
Oxidoreductases
ACE inhibitor
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Bibliography:ark:/67375/TPS-GPS2K3JV-G
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ISSN:0022-2623
1520-4804
DOI:10.1021/jm020424z