Cobalt-Catalyzed Carbonylation of C(sp2)–H Bonds with Azodicarboxylate as the Carbonyl Source

• Published in: Organic letters Vol. 18; no. 22; pp. 5960 - 5963
• Main Authors: Ni, Jiabin, Li, Jie, Fan, Zhoulong, Zhang, Ao
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 18.11.2016; Amer Chemical Soc
• Subjects: benzamides; catalysts; chemical reactions; Chemistry; Chemistry, Organic; cobalt; moieties; Physical Sciences; Science & Technology; FUNCTIONALIZATION; ACTIVATION; AMINATION; C-H BOND; ANNULATION; ARENES; TERMINAL ALKYNES; ETHOXYCARBONYLATION; ACCESS; AMIDES

A novel and efficient approach for the C­(sp2)–H bond carbonylation of benzamides has been developed using stable and inexpensive Co­(OAc)2·4H2O as the catalyst and the commercially available and easily handling azodicarboxylates as the nontoxic carbonyl source. A broad range of substrates bearing d...