Natural Occurrence, Syntheses, and Applications of Cyclopropyl-Group-Containing α-Amino Acids. 1. 1-Aminocyclopropanecarboxylic Acid and Other 2,3-Methanoamino Acids

The chemical synthesis, biological properties and pharmacology of 1-aminocyclopropanecarboxylic acid (ACC) is discussed. Compounds in this chemical family exhibit a variety of properties, from antidepressants to antibiotics.

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Bibliographic Details
Published inChemical reviews Vol. 107; no. 11; pp. 4493 - 4537
Main Authors Brackmann, Farina, de Meijere, Armin
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 01.11.2007
Subjects
Acids
Amino Acids - chemical synthesis
Amino Acids - chemistry
Amino Acids - pharmacology
Antiviral Agents - chemical synthesis
Antiviral Agents - pharmacology
Biochemistry
Carboxylic Acids - chemistry
Carboxylic Acids - pharmacology
Chemical compounds
Chemical Phenomena
Chemical synthesis
Chemistry, Physical
Cyclopropanes - chemistry
Cyclopropanes - pharmacology
Enzyme Inhibitors - chemical synthesis
Enzyme Inhibitors - pharmacology
Indicators and Reagents
Peptides - chemical synthesis
Pharmacology
Stereoisomerism
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Summary:The chemical synthesis, biological properties and pharmacology of 1-aminocyclopropanecarboxylic acid (ACC) is discussed. Compounds in this chemical family exhibit a variety of properties, from antidepressants to antibiotics.
Bibliography:istex:623B183B2E8A0E0DE2D36B0E90C4B1E90E03D028
ark:/67375/TPS-FCM0D50G-K
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0009-2665
1520-6890
DOI:10.1021/cr078376j