Direct Asymmetric Aldol Reactions of Acetone Using Bimetallic Zinc Catalysts

The enantioselective aldol reaction using a novel binuclear zinc catalyst of acetone with several aldehydes gave products in good yields (62−89%) with a high level of enantioselectivity (ee = 76−92%).

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Bibliographic Details
Published inOrganic letters Vol. 3; no. 16; pp. 2497 - 2500
Main Authors Trost, Barry M, Silcoff, Elliad R, Ito, Hisanaka
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 09.08.2001
Amer Chemical Soc
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Summary:The enantioselective aldol reaction using a novel binuclear zinc catalyst of acetone with several aldehydes gave products in good yields (62−89%) with a high level of enantioselectivity (ee = 76−92%).
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ISSN:1523-7060
1523-7052
DOI:10.1021/ol0161211