Nonreceptor Tyrosine Phosphatases in Cellular Signaling:  Regulation of Mitogen-Activated Protein Kinases

A large number of nonreceptor tyrosine phosphatases have been shown to specifically regulate mitogen-activated protein kinase (MAPK) signaling. Zhan, et al, provide an overview of MAPK signaling and then discuss the functions of intracellular PTPases, particularly the functions of PTPases in MAPK re...

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Published inChemical reviews Vol. 101; no. 8; pp. 2477 - 2496
Main Authors Zhan, Xiao-Li, Wishart, Matthew J, Guan, Kun-Liang
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 01.08.2001
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Summary:A large number of nonreceptor tyrosine phosphatases have been shown to specifically regulate mitogen-activated protein kinase (MAPK) signaling. Zhan, et al, provide an overview of MAPK signaling and then discuss the functions of intracellular PTPases, particularly the functions of PTPases in MAPK regulation.
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ark:/67375/TPS-WZF3SNJ3-3
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SourceType-Scholarly Journals-1
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ISSN:0009-2665
1520-6890
DOI:10.1021/cr000245u