Dopamine - Glutamate Interactions in the Basal Ganglia

The basal ganglia are involved in complex brain functions and are implicated in numerous neurological and psychiatric disorders. At the heart of both function and dysfunction of basal ganglia circuits is the interaction of dopamine and glutamate. Improved labeling, imaging, recording, and genetic ma...

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Bibliographic Details
Main Author Jones, Susan
Format eBook
LanguageEnglish
Published United States CRC Press 2016
Taylor & Francis Group
Edition1
SeriesFrontiers in Neuroscience
Subjects
Basal ganglia
Dopamine
Glutamic acid
Human anatomy, cytology, histology
D2 Receptor
AMPA Receptor Subunit
Group II
CS Neuron
Rat D1
LTP Induction
Dopamine Neurons
Basal Ganglia Motor Circuit
DA Neuron
mGluR Agonists
Group Iii
Dopamine Depletion
Group II mGluR
Glutamatergic Synapses
D2 Cell
D1 Inhibition
SNc Neuron
CB1 Receptor
Dorsal Striatum
D2 Receptor Activation
VTA Dopamine Neuron
SNr
AMPA Receptor
NMDA Receptor
mGluR4
Online AccessGet full text
ISBN9781420088809
1420088807
1420088793
9781420088793
DOI10.1201/b11284

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Summary:The basal ganglia are involved in complex brain functions and are implicated in numerous neurological and psychiatric disorders. At the heart of both function and dysfunction of basal ganglia circuits is the interaction of dopamine and glutamate. Improved labeling, imaging, recording, and genetic manipulation approaches have yielded new information on how dopamine and glutamate interact to generate the circuit activity underpinning basal ganglia function. This volume synthesizes this research, presenting current insights on individual neurons and synapses, detailed circuit analysis, and learning and action functions of the basal ganglia. The book also discusses compromised dopamine-glutamate interaction in various disorders of basal ganglia function.
ISBN:9781420088809
1420088807
1420088793
9781420088793
DOI:10.1201/b11284