Mild and Selective Oxygenation of Sulfides to Sulfoxides and Sulfones by Perfluoro-cis-2,3-dialkyloxaziridines
Sulfides are oxidized to sulfoxides by stoichiometric amounts of perfluoro-cis-2,3-dialkyloxaziridines 2. The reactions proceed at -40 degrees C with nearly complete selectivity and very good yields. Sulfoxides are also oxidized easily by 2 under mild conditions to corresponding sulfones. The oxidat...
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Published in | Journal of organic chemistry Vol. 59; no. 10; pp. 2762 - 2765 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
WASHINGTON
American Chemical Society
01.05.1994
Amer Chemical Soc |
Subjects | |
Online Access | Get full text |
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Summary: | Sulfides are oxidized to sulfoxides by stoichiometric amounts of perfluoro-cis-2,3-dialkyloxaziridines 2. The reactions proceed at -40 degrees C with nearly complete selectivity and very good yields. Sulfoxides are also oxidized easily by 2 under mild conditions to corresponding sulfones. The oxidation of some bioactive sulfides (promazine, albendazole, biotin, and others) is also reported. |
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Bibliography: | istex:4E402311C7B1EBC32668A555C26A7C39531B1D8A ark:/67375/TPS-FTD20HT0-Z |
ISSN: | 0022-3263 1520-6904 |
DOI: | 10.1021/jo00089a020 |