Electrocatalytic (Bio)Nanostructures Based on Polymer-Grafted Platinum Nanoparticles for Analytical Purpose

Functionalized platinum nanoparticles (PtNPs) possess electrocatalytic properties toward H2O2 oxidation, which are of great interest for the construction of electrochemical oxidoreductase-based sensors. In this context, we have shown that polymer-grafted PtNPs could efficiently be used as building b...

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Bibliographic Details
Published inACS applied materials & interfaces Vol. 8; no. 23; pp. 14747 - 14755
Main Authors Gal, François, Challier, Lylian, Cousin, Fabrice, Perez, Henri, Noel, Vincent, Carrot, Geraldine
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 15.06.2016
Washington, D.C. : American Chemical Society
Subjects
Chemical Sciences
Material chemistry
platinum nanoparticles
amperometric biosensor
neutron reflectivity
Langmuir−Blodgett films
polymer brushes
glucose oxidase
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Summary:Functionalized platinum nanoparticles (PtNPs) possess electrocatalytic properties toward H2O2 oxidation, which are of great interest for the construction of electrochemical oxidoreductase-based sensors. In this context, we have shown that polymer-grafted PtNPs could efficiently be used as building bricks for electroactive structures. In the present work, we prepared different 2D-nanostructures based on these elementary bricks, followed by the subsequent grafting of enzymes. The aim was to provide well-defined architectures to establish a correlation between their electrocatalytic properties and the arrangement of building bricks. Two different nanostructures have been elaborated via the smart combination of surface initiated-atom transfer radical polymerization (SI-ATRP), functionalized PtNPs (Br-PtNPs) and Langmuir–Blodgett (LB) technique. The first nanostructure (A) has been elaborated from LB films of poly­(methacrylic acid)-grafted PtNPs (PMAA-PtNPs). The second nanostructure (B) consisted in the elaboration of polymer brushes (PMAA brushes) from Br-PtNPs LB films. In both systems, grafting of the glucose oxidase (GOx) has been performed directly to nanostructures, via peptide bonding. Structural features of nanostructures have been carefully characterized (compression isotherms, neutron reflectivity, and profilometry) and correlated to their electrocatalytic properties toward H2O2 oxidation or glucose sensing.
ISSN:1944-8244
1944-8252
DOI:10.1021/acsami.6b02956