Non-Alcoholic Fatty Pancreas Disease is Associated with SYNTAX Score in Acute Coronary Syndrome

• Published in: Acta Cardiologica Sinica Vol. 38; no. 6; pp. 683 - 690
• Main Authors: Sahin, Sinan, Yerlikaya, M Gokhan, Ozderya, Ahmet, Cavusoglu, I Gokhan, Karadeniz, Aysegul, Turan, Turhan, Cirakoglu, Omer Faruk, Karal, Huseyin, Akyuz, Ali Riza, Kul, Selim, Sayin, M Rasit
• Format: Journal Article
• Language: English
• Published: 中華民國心臟學會 01.11.2022; Taiwan Society of Cardiology
• Subjects: Coronary Artery Disease; Original; SYNTAX score; Non-alcoholic fatty pancreas disease; Acute coronary syndrome; Ectopic adipose tissue; Atherosclerosis
• ISSN: 1011-6842
• DOI: 10.6515/ACS.202211_38(6).20220424A

Background: Evidence that individuals with excess fat in the pancreas have an increased risk of cardiovascular disease has been growing recently. Risk evaluation in acute coronary syndrome (ACS) patients plays a crucial role for both prognosis prediction and decision-making. Aim: The main aim of this study was to investigate the relationship between non-alcoholic fatty pancreas disease (NAFPD) and the complexity and severity of coronary artery disease as assessed using the SYNTAX score (SXscore) in ACS patients. Methods: A total of 99 consecutive patients with a first-time diagnosis of ACS were recruited. NAFPD was evaluated using transabdominal ultrasonography (TUS). SXscore was calculated using the SXscore algorithm. Results: The patients with NAFPD had a significantly higher SXscore than those without NAFPD (12.3 ± 6.4 and 8.2 ± 4.3, p ＜ 0.001). Univariable analysis showed that hypertension (p = 0.033) and presence of NAFPD (p = 0.001) were associated with increased SXscore. Moreover, multivariable analysis showed that the presence of NAFPD (p = 0.002) was associated with increased SXscore. Conclusions: NAFPD is easily detected by TUS. The presence of NAFPD in ACS patients may be a warning signal of complexity and severity of coronary artery disease.