Regional cerebral blood flow in schizophrenia

Regional cerebral blood flow (rCBF) was measured via xenon133 inhalation technique in 23 patients with schizophrenia and 18 age- and sex-matched controls. The mean blood flow to both hemispheres was found to be lower for the patients. The patients and their controls did not differ on interhemispheri...

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Bibliographic Details
Published inArchives of general psychiatry Vol. 39; no. 10; p. 1121
Main Authors Mathew, R J, Duncan, G C, Weinman, M L, Barr, D L
Format Journal Article
LanguageEnglish
Published United States 01.10.1982
Subjects
Adult
Cerebral Cortex - blood supply
Cerebrovascular Circulation
Female
Functional Laterality
Hallucinations - physiopathology
Humans
Male
Schizophrenia - physiopathology
Schizophrenia, Paranoid - physiopathology
Schizophrenic Psychology
Xenon Radioisotopes
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Summary:Regional cerebral blood flow (rCBF) was measured via xenon133 inhalation technique in 23 patients with schizophrenia and 18 age- and sex-matched controls. The mean blood flow to both hemispheres was found to be lower for the patients. The patients and their controls did not differ on interhemispheric differences in blood flow. There were no differences in rCBF between medicated and unmedicated, subchronic and chronic, and paranoid and nonparanoid patients. Hallucinations were associated with reduced blood flow to several postcentral regions.
ISSN:0003-990X
DOI:10.1001/archpsyc.1982.04290100001001