Radiation-related thyroid carcinoma

Of 1,825 subjects with a history of head or neck irradiation, 358 (19.6%) were found to have thyroid abnormalities. One hundred sixty-five (9%) had either single or multiple nodules 153 (8.4%) had diffuse thyromegaly, and 40 (2.2%) had had thyroid surgery. Surgery was performed on 113 subjects with...

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Bibliographic Details
Published inArchives of surgery (Chicago. 1960) Vol. 113; no. 9; p. 1072
Main Authors Cerletty, J M, Guansing, A R, Engbring, N H, Hagen, T C, Kim, H J, Shetty, K R, Rosenfeld, P S, Wilson, S
Format Journal Article
LanguageEnglish
Published United States 01.09.1978
Subjects
Adult
Child
Female
Humans
Male
Neoplasms, Radiation-Induced - diagnostic imaging
Neoplasms, Radiation-Induced - etiology
Neoplasms, Radiation-Induced - surgery
Radionuclide Imaging
Radiotherapy - adverse effects
Thyroid Neoplasms - diagnostic imaging
Thyroid Neoplasms - etiology
Thyroid Neoplasms - surgery
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Summary:Of 1,825 subjects with a history of head or neck irradiation, 358 (19.6%) were found to have thyroid abnormalities. One hundred sixty-five (9%) had either single or multiple nodules 153 (8.4%) had diffuse thyromegaly, and 40 (2.2%) had had thyroid surgery. Surgery was performed on 113 subjects with nodules; carcinoma was found in 34 (30.1%). Clinical examination of the neck was the most valuable method of detecting abnormalities. Detection of nodules was not significantly enhanced by routine use of thyroid imaging studies. Measurements of levels of serum thyroid-stimulating hormone, thyroxine, triidothyronine resin uptake, and thyroid antibodies were not useful in screening for nodules or carcinoma.
ISSN:0004-0010
DOI:10.1001/archsurg.1978.01370210054007