Delayed fatal outcome after possible Ru-Tuss overdose

Death resulted from the delayed onset of the acute respiratory distress syndrome and disseminated intravascular coagulation with left ventricular mural thrombus formation and nonbacterial thrombotic endocarditis approximately five days after an alleged attempted suicide by the ingestion of ten to tw...

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Bibliographic Details
Published inJournal of forensic sciences Vol. 25; no. 2; p. 349
Main Author Patterson, F K
Format Journal Article
LanguageEnglish
Published United States 01.04.1980
Subjects
Adult
Belladonna Alkaloids - poisoning
Chlorpheniramine - poisoning
Delayed-Action Preparations
Drug Combinations - poisoning
Female
Histamine H1 Antagonists - poisoning
Humans
Phenylephrine - poisoning
Phenylpropanolamine - poisoning
Respiratory Distress Syndrome, Adult - chemically induced
Vasoconstrictor Agents - poisoning
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Summary:Death resulted from the delayed onset of the acute respiratory distress syndrome and disseminated intravascular coagulation with left ventricular mural thrombus formation and nonbacterial thrombotic endocarditis approximately five days after an alleged attempted suicide by the ingestion of ten to twelve prolonged-action Ru-Tuss tablets. Although these lesions are thought to be similar in pathogenesis, this combination has not been previously reported in association with a drug overdose. The delay in onset is also of interest because of its clinical implications.
ISSN:0022-1198
DOI:10.1520/JFS12134J