Antitumor Agents, 110, Bryophyllin B, a Novel Potent Cytotoxic Bufadienolide from Bryophyllum pinnatum
Bryophyllin B [1], a potent cytotoxic bufadienolide, has been isolated from Bryophyllum pinnatum and its structure confirmed by the use of 2D-nmr techniques and difference nOe method. Transformation of bryotoxin C [2] to 1 with acid is also discussed.
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| Published in | Journal of natural products (Washington, D.C.) Vol. 52; no. 5; pp. 1071 - 1079 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
American Chemical Society
01.09.1989
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Bryophyllin B [1], a potent cytotoxic bufadienolide, has been isolated from Bryophyllum pinnatum and its structure confirmed by the use of 2D-nmr techniques and difference nOe method. Transformation of bryotoxin C [2] to 1 with acid is also discussed. |
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| AbstractList | Bryophyllin B [1], a potent cytotoxic bufadienolide, has been isolated from Bryophyllum pinnatum and its structure confirmed by the use of 2D-nmr techniques and difference nOe method. Transformation of bryotoxin C [2] to 1 with acid is also discussed. |
| Author | Yamagishi, Takashi Yan, Xiu-Zhen Chang, Jer-Jang Haruna, Mitsumasa Lee, Kuo-Hsiung |
| Author_xml | – sequence: 1 givenname: Takashi surname: Yamagishi fullname: Yamagishi, Takashi – sequence: 2 givenname: Mitsumasa surname: Haruna fullname: Haruna, Mitsumasa – sequence: 3 givenname: Xiu-Zhen surname: Yan fullname: Yan, Xiu-Zhen – sequence: 4 givenname: Jer-Jang surname: Chang fullname: Chang, Jer-Jang – sequence: 5 givenname: Kuo-Hsiung surname: Lee fullname: Lee, Kuo-Hsiung |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/2607348$$D View this record in MEDLINE/PubMed |
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| SubjectTerms | AGENTES ANTINEOPLASTICOS ANTINEOPLASTIC AGENTS Antineoplastic Agents, Phytogenic - isolation & purification Bufanolides - isolation & purification Bufanolides - pharmacology CRASSULACEAE Drug Screening Assays, Antitumor Magnetic Resonance Spectroscopy MEDICAMENT CYTOSTATIQUE Molecular Structure Plants - analysis TOXICIDAD TOXICITE TOXICITY Tumor Cells, Cultured |
| Title | Antitumor Agents, 110, Bryophyllin B, a Novel Potent Cytotoxic Bufadienolide from Bryophyllum pinnatum |
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