Inhibition of deoxyribonucleic acid polymerases from murine cells and oncornavirus by 5-alkylated derivatives of 1-.beta.-D-arabinofuranosyluracil 5'-triphosphate: substituent effects on inhibitory action

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Bibliographic Details
Published inBiochemistry (Easton) Vol. 20; no. 17; pp. 5088 - 5093
Main Authors Ono, Katsuhiko, Ohashi, Atsuko, Ogasawara, Masako, Matsukage, Akio, Takahashi, Taijo, Nakayama, Chikao, Saneyoshi, Mineo
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 18.08.1981
Subjects
Animals
Arabinonucleotides - pharmacology
Cell Line
DNA Polymerase I - antagonists & inhibitors
DNA Polymerase II - antagonists & inhibitors
DNA Polymerase III - antagonists & inhibitors
Kinetics
Mice
Nucleic Acid Synthesis Inhibitors
Plasmacytoma
Retroviridae - enzymology
Spectrophotometry, Ultraviolet
Structure-Activity Relationship
Templates, Genetic
Uracil Nucleotides - pharmacology
Uridine Triphosphate - analogs & derivatives
Uridine Triphosphate - pharmacology
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ark:/67375/TPS-P7C1Z05J-P
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0006-2960
1520-4995
DOI:10.1021/bi00520a040