Conformational analysis of podophyllotoxin and its congeners. Structure-activity relationship in microtubule assembly

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Bibliographic Details
Published inJournal of medicinal chemistry Vol. 22; no. 3; pp. 215 - 221
Main Authors Brewer, C. Fred, Loike, John D, Horwitz, Susan B, Sternlicht, Himan, Gensler, Walter J
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 01.03.1979
Subjects
Animals
Brain - ultrastructure
In Vitro Techniques
Magnetic Resonance Spectroscopy
Microtubules - drug effects
Microtubules - metabolism
Molecular Conformation
Podophyllotoxin - analogs & derivatives
Podophyllotoxin - analysis
Podophyllotoxin - pharmacology
Structure-Activity Relationship
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Bibliography:istex:E005CA87989B8B1D271EF2D3F48D7C5F58C081CA
ark:/67375/TPS-LBN3N20K-Z
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0022-2623
1520-4804
DOI:10.1021/jm00189a001