Solid-Supported tert-Alkoxycarbonylation Reagents for Anchoring of Amines during Solid Phase Organic Synthesis

The preparation and characterization of a homologous series of solid phase synthesis resins for anchoring amines via a Boc-like linker are described. The scope and limitations of these resins are explored with respect to procedures for attachment and cleavage of a variety of primary amines, secondar...

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Bibliographic Details
Published inJournal of organic chemistry Vol. 62; no. 10; pp. 3153 - 3157
Main Authors Hernández, Andrés S, Hodges, John C
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 16.05.1997
Amer Chemical Soc
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
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Summary:The preparation and characterization of a homologous series of solid phase synthesis resins for anchoring amines via a Boc-like linker are described. The scope and limitations of these resins are explored with respect to procedures for attachment and cleavage of a variety of primary amines, secondary amines, and α-amino esters.
Bibliography:istex:5E4BA1C087F1390C299CB8F9FFD083C73691372A
ark:/67375/TPS-Z428XLCD-F
Abstract published in Advance ACS Abstracts, May 1, 1997.
ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
ISSN:0022-3263
1520-6904
DOI:10.1021/jo9700890