Synthesis of (±)-Puraquinonic Acid:  An Inducer of Cell Differentiation

Puraquinonic acid (1) was synthesized from 2,5-dimethoxybenzoic acid by way of isochroman 2 and the indanone derivative 3, a Nazarov cyclization being used to construct the five-membered ring.

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Bibliographic Details
Published inJournal of organic chemistry Vol. 66; no. 3; pp. 954 - 961
Main Authors Clive, Derrick L. J, Sannigrahi, Mousumi, Hisaindee, Soleiman
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 09.02.2001
Amer Chemical Soc
Subjects
Cell Division - drug effects
Chemistry
Chemistry, Organic
Indenes - chemical synthesis
Physical Sciences
Science & Technology
Spectrum Analysis
ETHERS
AGENTS
CARBON
LEUKEMIA
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Summary:Puraquinonic acid (1) was synthesized from 2,5-dimethoxybenzoic acid by way of isochroman 2 and the indanone derivative 3, a Nazarov cyclization being used to construct the five-membered ring.
Bibliography:ark:/67375/TPS-Z64SQWGS-Q
istex:2DF978D2061741D2274552D9F972808C9603AC02
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0022-3263
1520-6904
DOI:10.1021/jo001523s