A Novel Class of Non-Peptidic Endothelin Antagonists Isolated from the Medicinal Herb Phyllanthus niruri

• Published in: Journal of natural products (Washington, D.C.) Vol. 58; no. 10; pp. 1515 - 1520
• Main Authors: Hussain, Raouf A, Dickey, Joyce K, Rosser, Mary P, Matson, James A, Kozlowski, Michael R, Brittain, Russell J, Webb, Maria L, Rose, Patricia M, Fernandes, Prabhavathi
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 01.10.1995; Glendale, AZ American Society of Pharmacognosy
• Subjects: Biological and medical sciences; CHEMICAL COMPOSITION; COMPOSICION QUIMICA; COMPOSITION CHIMIQUE; EPITELIO; EPITHELIUM; General pharmacology; HYPOPHYLLANTHIN; INDE; INDIA; LIGNANS; LIGNINAS; LIGNINE; LIGNINS; Medical sciences; MEDICINAL PROPERTIES; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NIRTETRALIN; PEPTIDE; PEPTIDES; PEPTIDOS; Pharmacognosy. Homeopathy. Health food; Pharmacology. Drug treatments; PHYLLANTHIN; PHYLLANTHUS; PROPIEDADES MEDICINALES; PROPRIETE PHARMACOLOGIQUE; Asia; India; Endothelin; Rat; Non peptide compound; Oxygen heterocycle; Medicinal plant; Dicotyledones; Angiospermae; Peptidergic receptor; Euphorbiaceae; Lignan; Aromatic compound; Antagonist; Hypophyllanthin; Pharmacognosy; Rodentia; In vitro; Biological activity; Vertebrata; Mammalia; Animal; Plant origin; Isolation; Above ground plant part; Spermatophyta; Structural analysis
• ISSN: 0163-3864; 1520-6025
• DOI: 10.1021/np50124a006