Time to Overcome the High, Long, and Bumpy Free Energy Barrier in a Multi-Stage Process: The Generalized Steady-State Approach

This paper presents a simple but general analytical estimate of the characteristic time of crossing a long, high, and arbitrary bumpy free energy barrier in the course of a sequential (one-dimensional) chemical, biochemical, or physical reaction. This estimate is based on a generalized steady-state...

Full description

Saved in:
Bibliographic Details
Published inThe journal of physical chemistry. B Vol. 119; no. 1; pp. 158 - 163
Main Author Finkelstein, Alexei V
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 08.01.2015
Subjects
Barriers
Biochemistry
Estimates
Free energy
Mathematical analysis
Physical chemistry
Thermodynamics
Time Factors
Online AccessGet full text

Cover

More Information
Summary:This paper presents a simple but general analytical estimate of the characteristic time of crossing a long, high, and arbitrary bumpy free energy barrier in the course of a sequential (one-dimensional) chemical, biochemical, or physical reaction. This estimate is based on a generalized steady-state approach developed in this paper.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1520-6106
1520-5207
DOI:10.1021/jp5109703