X‑ray Crystallography Analysis of Complexes Synthesized with Tris(2-pyridylmethyl)amine: A Laboratory Experiment for Undergraduate Students Integrating Interdisciplinary Concepts and Techniques

• Published in: Journal of chemical education Vol. 95; no. 5; pp. 876 - 881
• Main Authors: Bazley, Isabel J, Erie, Ellen A, Feiereisel, Garrett M, LeWarne, Christopher J, Peterson, Jack M, Sandquist, Katherine L, Oshin, Kayode D, Zeller, Matthias
• Format: Journal Article
• Language: English
• Published: Easton American Chemical Society and Division of Chemical Education, Inc 08.05.2018; Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society; American Chemical Society
• Subjects: Chemical synthesis; Chemistry; College Science; College students; Coordination compounds; Crystallography; Curricula; Hands on Science; Inorganic chemistry; Laboratories; Laboratory Experiments; Learning; Literature reviews; Molecular Structure; NMR; NMR spectroscopy; Nuclear magnetic resonance; Organic chemistry; Reaction mechanisms; Science Experiments; Science Instruction; Science Laboratories; Scientific Concepts; Spectroscopy; Undergraduate Study; NMR Spectroscopy; Upper-Division Undergraduate; Synthesis; Laboratory Instruction; Second-Year Undergraduate; Inorganic Chemistry; Hand-On Learning/Manipulatives; Crystals/Crystallography; Organic Chemistry
• ISSN: 0021-9584; 1938-1328
• DOI: 10.1021/acs.jchemed.7b00685

An integrated laboratory experiment applying concepts and techniques from organic chemistry, inorganic chemistry, and instrumental analysis is presented for use in the undergraduate curriculum. This experiment highlights the synthesis, characterization, and use of tris­(2-pyridylmethyl)­amine (TPMA) to make complexes with different metal salts. It incorporates laboratory practices such as literature searches, multistep synthesis, reaction mechanisms, NMR spectroscopy, and X-ray crystallography.