Involvement of Nervous System in Behcet's Syndrome

THE major features of Behçet's syndrome are recurrent oral and genital ulcers and ocular lesions.10 Many types of ocular involvement have been described, including uveitis, iridocyclitis with hypopyon, keratitis, optic neuritis, and inflammation, thrombosis, or hemorrhage of the blood vessels o...

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Published inArchives of neurology (Chicago) Vol. 12; no. 3; pp. 315 - 325
Main Authors WOLF, SHELDON M, SCHOTLAND, DONALD L, PHILLIPS, LOUISE L
Format Journal Article
LanguageEnglish
Published United States American Medical Association 01.03.1965
Subjects
Asthenia
Behcet Syndrome
Blood Cell Count
Blood Coagulation Tests
Cerebellar Diseases
Cerebrospinal Fluid
Diagnosis, Differential
Drug Therapy
Eyelids
Headache
Humans
Movement Disorders
Neurologic Manifestations
Old Medline
Ophthalmoplegia
Pathology
Prednisone - therapeutic use
Speech Disorders
Tremor
BEHCET'S SYNDROME
EYELIDS
BLOOD CELL COUNT
CEREBELLAR DISEASES
DRUG THERAPY
CEREBROSPINAL FLUID
MOVEMENT DISORDERS
OCULOMOTOR PARALYSIS
PATHOLOGY
TREMOR
HEADACHE
DIAGNOSIS, DIFFERENTIAL
ASTHENIA
PREDNISONE, THERAPEUTIC
SPEECH DISORDERS
BLOOD COAGULATION TESTS
NEUROLOGIC MANIFESTATIONS
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Summary:THE major features of Behçet's syndrome are recurrent oral and genital ulcers and ocular lesions.10 Many types of ocular involvement have been described, including uveitis, iridocyclitis with hypopyon, keratitis, optic neuritis, and inflammation, thrombosis, or hemorrhage of the blood vessels of the retina.57 Other manifestations of the syndrome have included pyoderma, furunculosis, erythema nodosum, thrombophlebitis, pericarditis, arthritis, hepatomegaly, epididymitis, ulcers of the gastrointestinal tract, and central nervous system disease. The etiology is not known.The disease may begin with any one of the triad of symptoms, and the complete syndrome may not appear until several years later.57 Curth23 has suggested that the diagnosis is justified when two of the three classic manifestatations are present; this principle has been accepted by others.26,56,58,90,92 Although the course is variable, the illness often abates in 15 to 20 years. Blindness is a frequent sequel.57 When neurologic complications are
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ISSN:0003-9942
1538-3687
DOI:10.1001/archneur.1965.00460270091012