Variables influencing the outcome following orthotopic liver transplantation

Seventy-two patients who underwent orthotopic liver transplantation (OLT) were studied to identify perioperative variables that would predict survival and intraoperative blood loss. Survival and intraoperative blood loss were not affected by encephalopathy, length of donor liver ischemia, or any of...

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Bibliographic Details
Published inArchives of surgery (Chicago. 1960) Vol. 122; no. 10; p. 1109
Main Authors Brems, J J, Hiatt, J R, Colonna, 2nd, J O, el-Khoury, G, Quiñones, W J, Ramming, K P, Ziomek, S, Busuttil, R W
Format Journal Article
LanguageEnglish
Published United States 01.10.1987
Subjects
Adolescent
Adult
Age Factors
Biliary Atresia - surgery
Blood Volume
Child
Child, Preschool
Female
Graft Rejection
Hemorrhage - etiology
Humans
Infant
Liver Transplantation
Male
Middle Aged
Portacaval Shunt, Surgical - adverse effects
Postoperative Complications
Postoperative Period
Renal Dialysis
Reoperation
Retrospective Studies
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Summary:Seventy-two patients who underwent orthotopic liver transplantation (OLT) were studied to identify perioperative variables that would predict survival and intraoperative blood loss. Survival and intraoperative blood loss were not affected by encephalopathy, length of donor liver ischemia, or any of the preoperative laboratory values studied. Survival was significantly decreased in patients requiring postoperative dialysis (41%) and in patients who had severe rejection requiring retransplantation (33%). Intraoperative blood loss was significantly greater in patients over 50 years of age (11.6 blood volumes) and patients with biliary atresia (8.7 blood volumes). These results may aid in choosing future recipients for orthotopic liver transplantation and in anticipating the postoperative support needed.
ISSN:0004-0010
1538-3644
DOI:10.1001/archsurg.1987.01400220019001