Tailoring Indocyanine Green J‑Aggregates for Imaging, Cancer Phototherapy, and Drug Delivery: A Review

Indocyanine green J-aggregates (ICG-Jagg) have emerged as a significant subject of interest in biomedical applications due to their unique optical properties, tunable size, and excellent biocompatibility. This comprehensive review aims to provide an in-depth exploration of ICG-Jagg, with a focus on...

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Published inACS applied bio materials Vol. 7; no. 8; pp. 5121 - 5135
Main Authors Kumari, Pooja, Arora, Smriti, Pan, Yuanwei, Ahmed, Ishtiaq, Kumar, Sumit, Parshad, Badri
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 19.08.2024
Subjects
Animals
Antineoplastic Agents - chemistry
Antineoplastic Agents - pharmacology
Biocompatible Materials - chemistry
Drug Delivery Systems
Humans
Indocyanine Green - chemistry
Materials Testing
Neoplasms - diagnostic imaging
Neoplasms - drug therapy
Neoplasms - therapy
Optical Imaging
Particle Size
Phototherapy
theranostics
phototherapy
J-aggregates
indocyanine green
bioimaging
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ISSN2576-6422
2576-6422
DOI10.1021/acsabm.4c00651

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Summary:Indocyanine green J-aggregates (ICG-Jagg) have emerged as a significant subject of interest in biomedical applications due to their unique optical properties, tunable size, and excellent biocompatibility. This comprehensive review aims to provide an in-depth exploration of ICG-Jagg, with a focus on elucidating the diverse facets of their preparation and the factors that influence the preparation process. Additionally, the review discusses their applications in biomedical diagnostics, such as imaging and contrast agents, as well as their utilization in drug delivery and various phototherapeutic interventions.
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ISSN:2576-6422
2576-6422
DOI:10.1021/acsabm.4c00651