A chemoenzymatic synthesis of leukotriene B4

A total synthesis of leukotriene B4 (1) is accomplished by the assembly of the key chirons 2 and 3, which are prepared via enzymatic methods.

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Bibliographic Details
Published inJournal of organic chemistry Vol. 51; no. 8; pp. 1253 - 1258
Main Authors Han, Chao Qi, DiTullio, Dennis, Wang, Yi Fong, Sih, Charles J
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 01.04.1986
Amer Chemical Soc
Subjects
Bioconversions. Hemisynthesis
Biological and medical sciences
Biotechnology
Chemistry
Chemistry, Organic
Fundamental and applied biological sciences. Psychology
Methods. Procedures. Technologies
Physical Sciences
Science & Technology
Stereochemistry
Arachidonic acid derivatives
Leucotriene B4
Hemisynthesis
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Summary:A total synthesis of leukotriene B4 (1) is accomplished by the assembly of the key chirons 2 and 3, which are prepared via enzymatic methods.
Bibliography:ark:/67375/TPS-L0LQRK0Z-6
istex:F2066FA5AD3F652ABAAEA2452FD3C4F3C93BCADB
ISSN:0022-3263
1520-6904
DOI:10.1021/jo00358a016