Barrett's esophagus: update on screening, surveillance, and treatment

The last 2 decades have seen dramatic advances in Barrett's esophagus. The definition has evolved; the rising incidence of adenocarcinoma has been recognized; and effective therapy to control gastroesophageal reflux disease has been developed. Both proton pump inhibitor therapy and laparoscopic...

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Bibliographic Details
Published inArchives of internal medicine (1960) Vol. 159; no. 13; p. 1411
Main Authors Morales, T G, Sampliner, R E
Format Journal Article
LanguageEnglish
Published United States 12.07.1999
Subjects
Adenocarcinoma - etiology
Barrett Esophagus - complications
Barrett Esophagus - diagnosis
Barrett Esophagus - prevention & control
Barrett Esophagus - therapy
Esophageal Neoplasms - etiology
Esophagoscopy
Humans
Mass Screening
Risk
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Summary:The last 2 decades have seen dramatic advances in Barrett's esophagus. The definition has evolved; the rising incidence of adenocarcinoma has been recognized; and effective therapy to control gastroesophageal reflux disease has been developed. Both proton pump inhibitor therapy and laparoscopic fundoplication represent major developments. Studies of patients with dysplasia have helped to clarify appropriate surveillance intervals and treatment strategies for these patients, although controversy still exists. The possibility of reversing Barrett's esophagus in selected high-risk patients offers major hope for the future prevention of adenocarcinoma of the esophagus.
ISSN:0003-9926
DOI:10.1001/archinte.159.13.1411